As their name suggests, polyprotic acids contain more than one acidic proton. The mass fraction of GA (wGA) ranged from (0 to 30.11) %. Glutarex ®-2 Amino acid-modified medical food. A small Ka value means little of the acid dissociates, so you have a weak acid. The value of K a is used to calculate the pH of weak acids.The pK a value is used to choose a buffer when needed. A large Ka value also means the formation of products in the reaction is favored. Choosing an acid or base where pK a is close to the pH needed gives the best results. Structure, properties, spectra, suppliers and links for: Glutaric acid, 110-94-1. Find here Glutaric Acid, 110-94-1 suppliers, manufacturers, wholesalers, traders with Glutaric Acid prices for buying. An acid dissociation constant, K a, is a quantitative measure of the strength of an acid in solution.It is the equilibrium constant for a chemical reaction known as dissociation of acid–base reactions. GA1 is an inherited disorder in which the body is unable to completely break down the amino acids lysine, hydroxylysine, and tryptophan due to a deficiency of mitochondrial glutaryl-CoA dehydrogenase (EC 1.3.99.7, GCDH). For a 0.10 M solution of glutaric acid, HO2C(CH2)3CO2H (Ka1 = 4.6 × 10–5, Ka2 = 3.9 × 10–6), rank the following species in order of increasing equilibrium concentration The copolymers of diacid, for example, glutaric acid, hexanedioic acid and decanedioic acid, with diols, for example, 1,3-propylene glycol, 1,4-butanediol and 1,6-hexanediol have heat-absorbing and -releasing properties. A large Ka value indicates a strong acid because it means the acid is largely dissociated into its ions. The molecular weight of Glutaric acid is 132.115 g/mol, while the boiling point of Glutaric acid is 579 ° F. Glutaric acid is partially soluble in water, and forms a moderately strong acid in water. Blockage at GCDH leads to accumulation of glutaric acid and 3-hydroxyglutaric acid in blood and urine. Chronically high levels of glutaconic acid are associated with glutaric aciduria type I (glutaric acidemia type I, glutaryl-CoA dehydrogenase deficiency, GA1, or GAT1). In aqueous solution, the equilibrium of acid dissociation can be written symbolically as: HA + H 2 O = A-+H 3 O + . An increased concentration of glutaric acid in the blood. The Ka Values For Glutaric Acid Are 4.52 × 10-5 (Ka1) And 3.78 × 10-6 (Ka2). Glutaric acid is the organic compound with the formula C 3 H 6 (COOH) 2.Although the related "linear" dicarboxylic acids adipic and succinic acids are water-soluble only to a few percent at room temperature, the water-solubility of glutaric acid is over 50% (w/w). All data apply to dilute aqueous solutions and are presented in the form of pK a , which is the negative of the logarithm of the acid dissociation constant K a . Glutaric acid is a pentanedioic acid. Baric I, Wagner L, Feyh P, Liesert M, Buckel W, Hoffmann GF. In order to provide thermodynamic data for mixed dibasic acid separation technology, the solubilities of adipic acid (AA) and succinic acid (SA) in glutaric acid (GA) + acetone mixture and GA + n-butanol mixture were measured by dynamic method at atmospheric pressure. Calculate the pH of a solution containing 0.0347 M glutaric acid and 0.020 M potassium hydrogen glutarate. Glutaric acid, also known as pentanedioic acid, is a carboxylic acid that is widely used for various applications including the production of polyesters, polyamides, polyurethanes, glutaric anhydride, 1,5-pentanediol, and 5-hydroxyvaleric acid. Chronically high levels of 3-hydroxyglutaric acid are associated with glutaric aciduria type I (glutaric acidemia type I, glutaryl-CoA dehydrogenase deficiency, GA1, or GAT1). The Ka value for most weak acids ranges from 10-2 to 10-14. Table of Acids with Ka and pKa Values* CLAS Acid HA A-Ka pKa Acid Strength Conjugate Base Strength Hydroiodic HI I-Hydrobromic HBr Br-Perchloric HClO4 ClO4-Hydrochloric HCl Cl-Chloric HClO3 ClO3-Sulfuric (1) H2SO4 HSO4-Nitric HNO3 NO3-Strong acids completely dissociate in aq solution (Ka > … HGEMP : Acylcarnitine analysis is included in newborn screening blood testing and is utilized for detection of several inborn errors of metabolism, including fatty acid oxidation disorders (FAOD) and organic acidemias (OA). See the answer. It is found that the cocrystal physically decomposes at 120 °C (i.e., in the range between the melting points of the two pure compounds). Get contact details & address of companies manufacturing and supplying Glutaric Acid, 110-94-1 across India. Glutaric acid (1,5-pentanedioic acid) is such an attractive building block for polymers. 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